Often asked: When to take simvastatin?

Which statins must be taken at bedtime?

To maximize the effects of statins with a short half-life, fluvastatin, lovastatin, and simvastatin should be dosed at bedtime allowing the greatest drug concentration to be present during peak endogenous cholesterol synthesis.

Can you take simvastatin on an empty stomach?

Take simvastatin on the evening, on an empty stomach. Shake the oral suspension well for at least 20 seconds before using it. Use a marked measuring spoon, oral syringe, or medicine cup to measure the right dose.

When is the best time to take cholesterol medication?

When to take medicine: Take statins at bedtime, advises the British Heart Foundation. Here’s why: Cholesterol production in the liver is highest after midnight and lowest during the morning and early afternoon, so statins are most effective when taken just before bedtime.

Does simvastatin make you sleepy?

In recent years, researchers discovered that people taking statins reported increased levels of general fatigue and tiredness, especially after exertion. A study from the University of California San Diego found that people taking statins experienced lower levels of energy than people who took a placebo.

Do statins age you faster?

So, while these findings are interesting and potentially important, there’s quite a large leap from these studies of minced fat cells to the conclusion that being treated with statins will lead a person to age prematurely.

What foods should be avoided when taking statins?

A: While taking atorvastatin (Lipitor), avoid high-fat and high-cholesterol foods as part of your overall treatment. You should avoid large quantities of grapefruit or grapefruit juice, which can increase the risk of serious side effects. Also, avoid excess alcohol use, as this may cause serious liver problems.

What can you not take with simvastatin?

Do not use more than 20 mg per day of simvastatin together with amiodarone (Cordarone®), amlodipine (Norvasc®), lomitapide (Juxtapid™), or ranolazine (Ranexa®). When used together with higher doses of simvastatin, these medicines may increase your risk of muscle injury and could result in kidney problems.

What medications should not be taken with simvastatin?

These drugs should not be used with simvastatin.

• ketoconazole.
• itraconazole.
• voriconazole.
• posaconazole.
• erythromycin.
• clarithromycin.
• telithromycin.
• cyclosporine.

What supplements should not be taken with simvastatin?

But that could be a bad idea. Statin drugs like Lipitor block the antioxidant effects of vitamin E, found in multivitamins, and vitamin E interferes with the health benefits of statins. These two guests need separate dinner dates.

Why do you have to take simvastatin at bedtime?

They act by inhibiting the enzyme HMG CoA reductase, which controls synthesis of cholesterol in the liver. Most manufacturers of statins recommend that they are taken at night, on the basis of physiological studies which show that most cholesterol is synthesised when dietary intake is at its lowest.

Why you should never take statins?

Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins.

What reduces cholesterol quickly?

Below are 10 natural ways to improve your cholesterol levels.

• Focus on Monounsaturated Fats.
• Use Polyunsaturated Fats, Especially Omega-3s.
• Avoid Trans Fats.
• Eat Soluble Fiber.
• Exercise.
• Lose weight.
• Don’t smoke.
• Use alcohol in moderation.

Can simvastatin keep you awake at night?

The top-selling statins are atorvastatin (Lipitor), lovastatin (Mevacor), rosuvastatin (Crestor) and simvastatin (Zocor). How they can cause insomnia: The most common side effect of all types of statins is muscle pain, which can keep people who take them awake at night and unable to rest.

Do statins make you pee more?

The study also found that statins were linked to fewer sleep disturbances, but an increase in reports of needing to urinate at night and urinate more frequently, while there were too few reports of cognitive problems to draw any conclusions.

Can you stop taking statins Once you start?

It’s possible for some people to stop taking statins safely, but it can be especially risky for others. For instance, if you have a history of heart attack or stroke, it’s not recommended that you stop taking these drugs. This is because you‘re more likely to have another such problem when you discontinue statins.